Prof. Joachim Schultze and his group at the LIMES Institute at the University of Bonn have been instrumental in a study that identified how "good cholesterol" - high density lipoprotein (HDL) - stops inflammation. Lead by immunologists at Prof. Latz's Institute of Innate Immunity, an international team of researchers from Australia, Japan, China, the USA and Germany have discovered transcriptional regulator, ATF3, as a factor responsible for the anti-inflammatory function of HDL. The findings have been published in the Journal NatureImmunology.
Publication: High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3, Nature Immunology, DOI:10.1038/ni.2784