[158] Schäfer, L., Miskey, C., Hein, S., Völker, E., Reuter, A., Beyer, K., Ahrens, B., Mayer, G. and Holzhauser, T. (2024). Dna meets protein─development, characterization, and application of aptamers against peanut allergen. Journal of Agricultural and Food Chemistry, 72(32), 18225–18233.

[157] Anna Jonczyk, Marlene Gottschalk, Matthew S J Mangan, Yasmin Majlesain, Manja W Thiem, Lea-Corinna Burbaum, Heike Weighardt, Eicke Latz, Günter Mayer, Irmgard Förster (2024). Topical application of a CCL22-binding aptamer suppresses contact allergy. Mol Ther Nucleic Acids. 2024 Jun 17;35(3):102254. doi: 10.1016/j.omtn.2024.102254. eCollection 2024 Sep 10

[156] Civit, L., Moradzadeh, N., Jonczyk, A., Neckermann, P., Asbach, B., Peterhoff, D., … Valero, J. (2024). A multi-faceted binding assessment of aptamers targeting the sars-cov-2 spike protein. International Journal of Molecular Sciences, 25(9), 4642. https://doi.org/10.3390/ijms25094642

[155] Legen, T., & Mayer, G. (2024). Modular approach for rapid identification of rna-based sensors. ACS Sensors, acssensors.3c02060. https://doi.org/10.1021/acssensors.3c02060

[154] Pietruschka, G., Ranzani, A. T., Weber, A., Patwari, T., Pilsl, S., Renzl, C., … Mayer, G. (2024). An rna motif that enables optozyme control and light‐dependent gene expression in bacteria and mammalian cells. Advanced Science, 2304519. https://doi.org/10.1002/advs.202304519

[153] Bjarne Silkenath, Dennis Kläge, Hanna Altwein, Nina Schmidhäuser, Günter Mayer, Jörg S Hartig, Valentin Wittmann (2023). Phosphonate and Thiasugar Analogues of Glucosamine-6-phosphate: Activation of the glmS Riboswitch and Antibiotic Activity. ACS Chem Biol. 2023 Oct 20;18(10):2324-2334. doi: 10.1021/acschembio.3c00452. Epub 2023 Oct 4

[152] Tugce Guel, Benedikt Scholtissek, Julia Siegl, Tanja Fetter, Günter Mayer, Thomas Bieber, Joerg Wenzel. Dermatomyositis autoantigen CHD4 forms immune stimulatory complexes with endogenous DNA. Experimental Dermatology. Published online March 30, 2023:exd.14799.

[151] David Stängle, Bjarne Silkenath, Paul Gehle, Anna Esser, Günter Mayer, Valentin Wittmann (2023). Carba-Sugar Analogs of Glucosamine-6-Phosphate: New Activators for the glmS Riboswitch. Chemistry. 2023 Jan 12;29(3):e202202378. doi: 10.1002/chem.202202378

[150] Breuers S, Mayer G. Methods Mol Biol. 2023;2570:3-11. doi: 10.1007/978-1-0716-2695-5_1. PMID: 36156770

[149] Otte DM, Choukeife M, Patwari T, Mayer G. Nucleic acid aptamers: from basic research to clinical applications. In: Sugimoto N, ed. Handbook of Chemical Biology of Nucleic Acids. Springer Nature Singapore; 2022:1-25.

[148] Esser A, Mayer G. Characterization of the glmS ribozymes from Listeria monocytogenes and Clostridium difficile. Chemistry. 2022 Oct 4. doi: 10.1002/chem.202202376. Epub ahead of print. PMID: 36194523.

[147] Choukeife M, Jonczyk A, Mayer G. Methods Mol Biol. 2023;2570:39-44. doi: 10.1007/978-1-0716-2695-5_3. PMID: 36156772

[146] Ranzani AT, Wehrmann M, Kaiser J, Juraschitz M, Weber AM, Pietruschka G, Gerken U, Mayer G, Möglich A. ACS Synth Biol. 2022 Sep 21. doi: 10.1021/acssynbio.2c00365. Online ahead of print. PMID: 36129831

[145] Maureen McKeague, Victoria Calzada, Laura Cerchia, Maria DeRosa, Jennifer M Heemstra, Nebojsa Janjic, Philip E Johnson, Leon Kraus, Janice Limson, Günter Mayer, Marit Nilsen-Hamilton, David Porciani, Tarun Kumar Sharma, Beatrix Suess, Julian A Tanner, Sarah Shigdar. The minimum aptamer publication standards (MAPS guidelines) for de novo aptamer selection. Aptamers, 2022, Vol 6, 10-18. ISSN 2514-3247

[144] Dietler J, Gelfert R, Kaiser J, Borin V, Renzl C, Pilsl S, Ranzani AT, Fuentes AG, Gleichmann T, Diensthuber RP, Weyand M, Mayer G, Schapiro I, Möglich A. Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine. Nat Commun. 2022 May 12. doi.org/10.1038/s41467-022-30252-4

[143] Hamedani NS, Happich FL, Klein EM, Rühl H, Mayer G, Oldenburg J, Müller J, Pötzsch B. Aptamer loaded superparamagnetic beads for selective capturing and gentle release of activated protein C. Sci Rep. 2022 Apr 30;12(1):7091. doi: 10.1038/s41598-022-11198-5

[142] Geraci I, Autour A, Pietruschka G, Shiian A, Borisova M, Mayer C, Ryckelynck M, Mayer G. Fluorogenic RNA-Based Biosensor to Sense the Glycolytic Flux in Mammalian Cells. ACS Chem Biol. 2022 Apr 15. doi: 10.1021/acschembio.2c00100. Online ahead of print. PMID: 35427113

[141] Seiler LK, Phung NL, Nikolin C, Immenschuh S, Erck C, Kaufeld J, Haller H, Falk CS, Jonczyk R, Lindner P, Thoms S, Siegl J, Mayer G, Feederle R, Blume CA. An Antibody-Aptamer-Hybrid Lateral Flow Assay for Detection of CXCL9 in Antibody-Mediated Rejection after Kidney Transplantation. Diagnostics (Basel). 2022 Jan 25;12(2):308. doi: 10.3390/diagnostics12020308. PMID: 35204399

[140] Siegl J, Nikolin C, Phung NL, Thoms S, Blume C, Mayer G. Split–Combine Click-SELEX Reveals Ligands Recognizing the Transplant Rejection Biomarker CXCL9. ACS Chem Biol. 2022 Jan 21;17(1):129-137. doi: 10.1021/acschembio.1c00789. Epub 2022 Jan 12. PMID: 35018777

[139] Siegl J, Plückthun O, Mayer G. Dependence of click-SELEX performance on the nature and average number of modified nucleotides. RSC Chem Biol. 2022 Feb 21;3(3):288-294. doi: 10.1039/d2cb00012a. eCollection 2022 Mar 9. PMID: 35359492

[138] Martínez-Roque MA, Franco-Urquijo PA, García-Velásquez VM, Choukeife M, Mayer G, Molina-Ramírez SR, Figueroa-Miranda G, Mayer D, Alvarez-Salas LM. DNA aptamer selection for SARS-CoV-2 spike glycoprotein detection. Anal Biochem. 2022 May 15;645:114633. doi: 10.1016/j.ab.2022.114633. Epub 2022 Mar 2. PMID: 35247355

[137] Müller P, Sahlbach M, Gasper S, Mayer G, Müller J, Pötzsch B, Heckel A. Controlling Coagulation in Blood with Red Light. Angew Chem Int Ed. 2021 Oct 4;60(41):22441-22446. doi: 10.1002/anie.202108468. Epub 2021 Aug 31. PMID: 34293228

[136] Alvaro Darío Ortega, Vakil Takhaveev, Silke Roelie Vedelaar, Yi Long, Neus Mestre-Farràs, Danny Incarnato, Franziska Ersoy, Lars Folke Olsen, Günter Mayer, Matthias Heinemann. A synthetic RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux. Cell Chem Biol. 2021 Apr 22;S2451-9456(21)00161-6.

[135] Anton Schmitz, Anna Weber, Mehtap Bayin, Stefan Breuers, Volkmar Fieberg, Michael Famulok, Günter Mayer. A SARS‐CoV‐2 Spike Binding DNA Aptamer that Inhibits Pseudovirus Infection by an RBD‐Independent Mechanism. Angew Chem Int Ed Engl. 2021 Mar 8. doi: 10.1002/anie.202100316

[134] Nasim Shahidi Hamedani, Arijit Biswas, Oliver Rudan, Rosa Tönges, Carlotta Meyring, Fabian Tolle, Günter Mayer, Johannes Oldenburg, Jens Müller, Bernd Pötzsch. Functional and Structural Characterization of Nucleic Acid Ligands That Bind to Activated Coagulation Factor XIII. J. Clin. Med. 2021 ;10(4), 677; https://doi.org/10.3390/jcm10040677.

[133] Renzl C, Kakoti A, Mayer G. Aptamer-Mediated Reversible Transactivation of Gene Expression by Light. Angew Chem Int Ed Engl. 2020 Dec 7;59(50):22414-22418. doi: 10.1002/anie.202009240.

[132] Plückthun O, Siegl J, Lledo Bryant L, Mayer G. Dynamic changes in DNA populations revealed by split-combine selection. Chem. Sci., 2020, 11, 9577-9583

[131] Pilsl S, Morgan C, Choukeife M, Möglich A, Mayer G. Optoribogenetic control of regulatory RNA molecules. Nat Commun. 2020 Sep 24;11(1):4825. doi: 10.1038/s41467-020-18673-5.

[130] Hamedani NS, Müller J, Tolle F, Rühl H, Pezeshkpoor B, Liphardt K, Oldenburg J, Mayer G, Pötzsch B. Selective Modulation of the Protease Activated Protein C Using Exosite Inhibiting Aptamers. Nucleic Acid Ther. 2020 Oct;30(5):276-288. doi: 10.1089/nat.2020.0844. Epub 2020 Jun 2. PMID: 32486960

[129] Mayer G, Legen T, Patwari T, Weber AM. Hunting Cells for Gentle Liberation. Cell Chem Biol. 2020 Mar 19;27(3):257-258. doi: 10.1016/j.chembiol.2020.02.006.

[128] Hornung T, O'Neill HA, Logie SC, Fowler KM, Duncan JE, Rosenow M, Bondre AS, Tinder T, Maher V, Zarkovic J, Zhong Z, Richards MN, Wei X, Miglarese MR, Mayer G, Famulok M, Spetzler D. ADAPT identifies an ESCRT complex composition that discriminates VCaP from LNCaP prostate cancer cell exosomes. Nucleic Acids Res. 2020 Jan 28. pii: gkaa034.

[127] Torres-Fernández LA, Jux B, Bille M, Port Y, Schneider K, Geyer M, Mayer G, Kolanus W. The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21. Nucleic Acids Res. 2019 Nov 16. pii: gkz1057.

[126] Drabik A, Ner-Kluza J, Piechura K, Mayer G, Silberring J. Changes in Protein Glycosylation as a Result of Aptamer Interactions with Cancer Cells. Proteomics Clin Appl. 2019 Sep 24:e1800186.

[125] Weber AM, Kaiser J, Ziegler T, Pilsl S, Renzl C, Sixt L, Pietruschka G, Moniot S, Kakoti A, Juraschitz M, Schrottke S, Lledo Bryant L, Steegborn C, Bittl R, Mayer G, Möglich A. A blue light receptor that mediates RNA binding and translational regulation. Nat Chem Biol. 2019 August 26;

[124] Stefan Breuers, Laura Lledo Bryant, Tjasa Legen, Günter Mayer. Robotic assisted generation of 2′-deoxy-2′-fluoro-modified RNA aptamers – High performance enabling strategies in aptamer selection. Methods 2019 May 15; Vol. 161, Pages 3-9

[123] Rosenthal M, Pfeiffer F, Mayer G. A receptor‐guided design strategy for ligand identification. Angew Chem Int Ed Engl. 2019 May 03;

[122] Haßel S, Mayer G. Aptamers as Therapeutic Agents: Has the Initial Euphoria Subsided? Mol Diagn Ther (pp 1-9). 2019 April 29;

[121] Rosenthal M, Pfeiffer F, Mayer G. Copper-Catalyzed Alkyne-Azide Cycloaddition on the Solid Phase for the Preparation of Fully Click-Modified Nucleic Acids. Methods Mol Biol. 2019; 1973:177-183

[120] Sonal S. Tonapi, Vaishali Pannu, Janet E. Duncan, Matthew Rosenow, Anthony Helmstetter, Daniel Magee, Qing Zhang, Teresa T. Tinder, Melissa Richards, David D. Halbert, Michael Famulok, David Spetzler, Mark R. Miglarese, Heather A. O'Neill, Günter Mayer. Translocation of a Cell Surface Spliceosomal Complex Induces Alternative Splicing Events and Lymphoma Cell Necrosis. Cell Chemical Biology 2019 Mar 28;

[119| Civit L., Theodorou I, Frey F, Weber H, Lingnau A, Gröber C, Blank M, Dambrune C, Stunden J, Beyer M, Schulze J, Latz E, Ducongé F, Kubbutat M, Mayer G. Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model. Sci Rep. 2019 Mar 21; 9:4976

[118] Ahmed S.M. Ali, Medhat S. El-Halawany, Sherif Abdelaziz Ibrahim, Olga Plückthun, Ahmed S.G. Khalil, Günter Mayer. Aptasensor for Quantifying Pancreatic Polypeptide. ACS Omega 2019; 4, 2, 2948-2956.

[117] Friedrich MJ, Schmolders J, Rommelspacher Y, Strauss A, Rühl H, Mayer G, Oldenburg J, Wirtz DC, Müller J, Pötzsch B. Activity Pattern Analysis Indicates Increased but Balanced Systemic Coagulation Activity in Response to Surgical Trauma. TH Open. 2018 Oct 1;2(4):e350-e356

[116] Pfeiffer F, Gröber C, Blank M, Händler K, Beyer M, Schultze JL, Mayer G. Systematic evaluation of error rates and causes in short samples in next-generation sequencing. Sci Rep. 2018 Jul 19; 8:10950.

[115] Pereira RL, Nascimento IC, Santos AP, Ogusuku IEY, Lameu C, Mayer G, Ulrich H. Aptamers: novelty tools for cancer biology. Oncotarget. 2018 Jun 1; 9(42):26934-26953.

[114] Drabik A, Ner-Kluza J, Mielczarek P, Civit L, Mayer G, Silberring J. Advances in the Study of Aptamer−Protein Target Identification Using the Chromatographic Approach. J Proteome Res. 2018 Jun 1; 17(6):2174-2181.

[113] Domenyuk V, Gatalica Z, Santhanam R, Wei X, Stark A, Kennedy P, Toussaint B, Levenberg S, Wang J, Xiao N, Greil R, Rinnerthaler G, Gampenrieder SP, Heimberger AB, Berry DA, Barker A, Quackenbush J, Marshall JL, Poste G, Vacirca JL, Vidal GA, Schwartzberg LS, Halbert DD, Voss A, Magee D, Miglarese MR, Famulok M, Mayer G & Spetzler D. Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes. Nat. Commun. 2018; 9:1219.

[112] Pfeiffer F, Tolle F, Rosenthal M, Brändle G, Ewers J, Mayer G. Identification and characterization of nucleobase-modified aptamers by click-SELEX. Nat. Protocols. 2018 May; 13(5):1153-1180.

[111] Fülle L, Steiner N, Funke M, Gondorf F, Pfeiffer F, Siegl J, Opitz FV, Haßel SK, Erazo AB, Schanz O, Stunden HJ, Blank M, Gröber C, Händler K, Beyer M, Weighardt H, Latz E, Schultze JL, Mayer G, Förster I. RNA Aptamers Recognizing Murine CCL17 Inhibit T Cell Chemotaxis and Reduce Contact Hypersensitivity In Vivo. Mol Ther. 2018 Jan 3; 26(1):95-104.

[110] Pfeiffer F, Rosenthal M, Siegl J, Ewers J, Mayer G. Customised nucleic acid libraries for enhanced aptamer selection and performance. Curr Opin Biotechnol. 2017 Dec; 48:111-118. 

[109] Mayer G, Möglich A. Editorial overview: Chemical biotechnology: Interdisciplinary approaches for the engineering of nucleic acids, proteins and cells. Curr. Opin. Biotechnol. 2017 Dec; 48:5–6.

[108] Civit L, Taghdisi SM, Jonczyk A, Haßel S, Gröber C, Blank M, Stunden HJ, Beyer M, Schultze J, Latz E, Mayer G. Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells. Biochimie. 2017 Oct 17; pii: S0300-9084(17)30259-6.

[107] Wolter O, Mayer G. Aptamers as Valuable Molecular Tools in Neurosciences. J Neurosci. 2017 Mar 8; 37(10):2517-2523.

[106] Ranches G, Lukasser M, Schramek H, Ploner A, Stasyk T, Mayer G, Mayer G, Hüttenhofer A. In Vitro Selection of Cell-Internalizing DNA Aptamers in a Model System of Inflammatory Kidney Disease. Mol Ther Nucleic Acids. 2017 Sep 15; 8:198-210.

[105] Matzner D, Schüller A, Seitz T, Wittmann V, Mayer G. Fluoro-Carba-Sugars are Glycomimetic Activators of the glmS Ribozyme. Chemistry. 2017 Sep 12; 23(51):12604-12612. 

[104] Schüller A, Matzner D, Lünse C. E, Wittmann V, Schumacher C, Unsleber S, Brötz-Oesterhelt H, Mayer C, Bierbaum G, Mayer G. Activation of the glmS ribozyme confers bacterial growth inhibition. Chembiochem. 2017 Mar 2; 18(5):435-440.

[103] Domenyuk V, Zhong Z, Stark A, Xiao N, O’Neill HA, Wei X, Wang J, Tinder TT, Tonapi S, Duncan J, Hornung T, Hunter A, Miglarese MR, Schorr J, Halbert DD, Quackenbush J, Poste G, Berry DA, Mayer G, Famulok M, Spetzler D. Plasma exosome profiling of cancer patients by a next generation systems biology approach. Sci. Rep. 2017 Feb 20; 7:42741.

[102] Lünse CE, Mayer G. Reporter Gene-Based Screening for TPP Riboswitch Activators. Methods Mol Biol. 2017; 1520:227-235.

[101] Seyfried P, Eiden L, Grebenovsky N, Mayer G, Heckel A. Photo-Tethers for the (Multi-)Cyclic, Conformational Caging of Long Oligonucleotides. Angew Chem Int Ed Engl. 2017 Jan 2; 56(1):359-363.

[100] Hamedani NS, Rühl H, Zimmermann JJ, Heiseler T, Oldenburg J, Mayer G, Pötzsch B, Müller J. In Vitro Evaluation of Aptamer-Based Reversible Inhibition of Anticoagulant Activated Protein C as a Novel Supportive Hemostatic Approach. Nucleic Acid Ther. 2016 Dec; 26(6):355-362.

[99] Pfeiffer F, Mayer G. Selection and Biosensor Application of Aptamers for Small Molecules. Front Chem. 2016 Jun 15; 4:25.

[98] Mayer G, Tolle F, Pfeiffer F, Rosenthal M. Click reaction on solid phase enables high fidelity synthesis of nucleobase-modified DNA. Bioconjug Chem. 2016 Feb 5.

[97] Jauset RM, Svobodová M, Mairal T, Schubert T, Künne S, Mayer G, O'Sullivan CK. β-Conglutin dual aptamers binding distinct aptatopes. Anal BioanalChem. 2016 Jan; 408(3):875-84.

[96] Müller J, Becher T, Mayer G, Pötzsch B. Aptamer-Based Enzyme Capture Assay for Measurement of Plasma Thrombin Levels. Methods Mol Biol. 2016; 1380:179-89.

[95] Tolle F, Mayer G. Preparation of SELEX Samples for Next-Generation Sequencing. Methods Mol Biol. 2016; 1380:77-84.

[94] Long Y, Pfeiffer F, Mayer G, Schrøder TD, Özalp VC, Olsen LF. Selection of Aptamers for Metabolite Sensing and Construction of Optical Nanosensors. Methods Mol Biol. 2016; 1380:3-19.

[93] Civit L, Pinto A, Rodrigues-Correia A, Heckel A, O'Sullivan CK, Mayer G. Sensitive detection of cancer cells using light-mediated apta-PCR. Methods. 2015 Nov 23. pii: S1046-2023(15)30158-4.

[92] Tolle F, Brändle GM, Matzner D, Mayer G. A Versatile Approach Towards Nucleobase-Modified Aptamers. Angew Chem Int Ed Engl. 2015 Sep 7;54(37):10971-4.

[91] Opazo F, Eiden L, Hansen L, Rohrbach F, Wengel J, Kjems J, Mayer G. Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer. MolTher Nucleic Acids. 2015 Sep 1;4:e251.

[90] Dickinson H, Lukasser M, Mayer G, Hüttenhofer A. Cell-SELEX: in vitro selection of synthetic small specific ligands. Methods Mol Biol. 2015; 1296:213-24.

[89] Lennarz S, Alich TC, Kelly T, Blind M, Beck H, Mayer G. Selective aptamer-based control of intraneuronal signaling. Angew Chem Int Ed Engl. 2015 Apr 27; 54(18):5369-73.

[88] Matzner D, Mayer G. (Dis)similar Analogues of Riboswitch Metabolites as Antibacterial Lead Compounds. J Med Chem. 2015 Apr 23; 58(8):3275-86.

[87] Hamedani NS, Blümke F, Tolle F, Rohrbach F, Rühl H, Oldenburg J, Mayer G, Pötzsch B, Müller J. Capture and Release (CaR): a simplified procedure forone-tube isolation and concentration of single-stranded DNA during SELEX. ChemCommun (Camb). 2015 Jan 21; 51(6):1135-8.

[86] Lennarz S, Heider E, Blind M, and Mayer G. An aptamer to the MAP kinase insert region. ACS Chem. Biol., 2015 Jan 16;10(1):320-7.

[85] Tolle F, Wilke J, Wengel J, Mayer G. By-product formation in repetitive PCR amplification of DNA libraries during SELEX. PLoS One. 2014 Dec 9; 9(12):e114693.

[84] Famulok M, Mayer G. Aptamers and SELEX in Chemistry & Biology. Chem Biol. 2014 Sep 18; 21(9):1055-8.

[83] Lünse CE, Scott FJ, Suckling CJ, and Mayer G. Novel TPP-riboswitch activators bypass metabolic enzyme dependency. Front. Chem., 2014, 2, 53.

[82] Pofahl M, Wengel J, and Mayer G. Multifunctional nucleic acids for tumour cell treatment. Nucleic Acid Ther., 2014, 24, 171-177.

[81] Yassin AA, Elwaseef AM, Elnashar M, Oldenburg J, Mayer G, Pötzsch B, and Müller J. Protamine-adsorbed magnetic nanoparticles for efficient isolation and concentration of hepatitis-C virus from human plasma samples. Chem. Com., 2014, 50, 590-592.

[80] Rohrbach F, Schäfer F, Fichte MAH, Pfeiffer F, Müller J, Pötzsch B, Heckel A, and Mayer G. Aptamer-guided caging for selective masking of protein domains. Angew. Chem. Int. Ed., 2013, 52, 1912-5

[79] Mayer G, Pofahl M, Schöler KMU, and Haßel S. Cell-specific aptamers for nano-medical applications. Nucleic Acid Nanotechnology, Springer-Verlag (Ed. J. Kjems), 2013.

[78] Lünse CE, Schüller A, and Mayer G. The promise of riboswitches as potential antibacterial drug targets. Int. J. Med. Microbiol., 2014, 304, 79-92.

[77] Hussein M, Bettio M, Schmitz A, Hannam JS, Theis J, Mayer G, Dosa S, Gütschow M, and Famulok M. Cyplecksins are covalent cytohesin pleckstrin homology domain inhibitors. Angew. Chem. Int. Ed., 2013, 52, 9529-9533.

[76] Lünse CE & Mayer G. Screening assays to identify artificial glmS ribozyme activators. Meth. In Mol. Biol., 2014, Springer Protocols, Humana Press Ltd. (Ed. Lafontaine).

[75] Magbanua E, Zivkovic T, Hansen B, Beschorner N, Meyer C, Lorenzen I, Grötzinger J, Hauber J, Torda A, Mayer G, Rose-John S, and Hahn U. d(GGGT)4 and r(GGGU)4 are both HIV-1 Inhibitors and Interleukin-6 Receptor Aptamers. RNA Biology, 2012, 10, 216-227.

[74] Lentz CS, Halls V, Hannam JS, Niebel B, Strübing U, Mayer G, Hoerauf A, Famulok M, and Pfarr K. A selective inhibitor of heme biosynthesis in endosymbiotic bacteria elicits antifilarial activity in vitro. Chem. Biol., 2013, 20, 177-187.

[73] Tolle F and Mayer G. Dressed for success - Applying chemistry to modulate aptamer functionality. Chem. Sci., 2013, 4, 60-67.

[72] Vinkenborg JL, Mayer G, and Famulok M. Aptamer-based affinity labeling of proteins, Angew. Chem. Int. Ed., 2012, 51, 9176-9180.

[71] Brieke C, Rohrbach F, Gottschalk A*, Mayer G*, and Heckel A*.  Light-controlled tools. Angew. Chem. Int. Ed., 2012, 51, 8446-8476.

[70] Rohrbach F, Fathalla MI, Kupper T, Pötzsch B, Müller J, Petersen M, Pedersen EB, and Mayer G. Chemical maturation of a bivalent aptamer by single domain variation. ChemBioChem, 2012, 13, 631-634.

[69] Rühl H, Müller J, Fimmers R, Harbrecht U, Oldenburg J, Mayer G, and Pötzsch B. Thrombin inhibition profiles in healthy individuals and thrombophilic patients. Thrombosis & Haemostasis, 2012, 107, 848-853.

[68] Tesmer VM, Lennarz S, Mayer G*, and Tesmer JJG*. Molecular mechanism for inhibition of G-protein coupled receptor kinase 2 by a selective RNA aptamer. Structure, 2012, 20, 1300-1309.

[67] Pinto A, Lennarz S, Rodrigues-Correia A, Heckel A, O’Sullivan CK, and Mayer G. Functional detection of proteins with caged aptamers. ACS Chem. Biol., 2012, 7, 360-366.

[66] Meyer C, Eydeler K, Magbanua E, Zivkovic T, Piganeau N, Lorenzen I, Grötzinger J, Mayer G, Rose-John S, and Hahn U. Interleukin-6 receptor specific RNA aptamers for cargo delivery into target cells. RNA Biol., 2012, 9, 67-80.

[65] Müller J, Becher T, Braunstein J, Berdel P, Gravius S, Rohrbach F, Oldenburg J, Mayer G,* and Pötzsch B*. Monitoring of plasma levels of activated protein C using a clinically applicable oligonucleotide-based enzyme capture assay (OECA), J. Thromb. Haemost., 2012, 10, 390-398.

[64] Rohrbach F, Karadeniz H, Erdem A*, Famulok M, and Mayer G*. Label-free Impedimetric Aptasensor for Lysozyme Detection Based on Carbon Nanotube Modified Screen Printed Electrodes. Anal. Biochem., 2012, 421, 454-459.

[63] Wulffen B, Buff MC, Pofahl M, Mayer G*, and Heckel A*. Caged glucosamine-6-phosphate for the light-control of riboswitch activity. Photochem. Photobiol. Sci., 2012, 11, 489-492.

[62] Mayer G, Lennarz S, Rohrbach F, and Tolle F. Plug and Play with RNA. Angew. Chem. Int. Ed., 2011, 50, 12400-1.

[61] Beyer M, Thabet Y, Müller RU, Sadlon T, Classen S, Lahl K, Basu S, Zhou X, Bailey-Bucktrout SL, Krebs W, Schönfeld EA, Böttcher J, Golovina T, Mayer CT, Hofmann A, Sommer D, Debey-Pascher S, Endl E, Limmer A, Hippen KL, Blazar BR, Balderas R, Quast T, Waha A, Mayer G, Famulok M, Knolle PA, Wickenhauser C, Kolanus W, Schermer B, Bluestone JA, Barry SC, Sparwasser T, Riley JL, Schultze J. Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat. Immunol., 2011, 12, 898-907.

[60] Famulok M and Mayer G. Aptamer modules as sensors and detectors. Acc. Chem. Res., 2011, 44, 1349-58.

[59] Mayer G, Rohrbach F, Pötzsch B, and Müller J. Aptamer-based modulation of blood coagulation. Hämostaseologie, 2011, 31, 258-63.

[58] Lünse CE, Schmidt M, Wittmann V, and Mayer G. Carba-sugars activate the glmS-riboswitch from Staphylococcus aureus. ACS Chem. Biol., 2011, 6, 675-678.

[57] Müller J, Becher T, Braunstein J, Berdel P, Gravius S, Rohrbach F, Oldenburg J, Mayer G,* and Pötzsch B*. Profiling of Active Thrombin in Human Blood by Supramolecular Complexes. Angew. Chem. Int. Ed., 2011, 50, 6075-8.

[56] Mayer G, Müller J, and Lünse CE. RNA diagnostics: real-time RT-PCR strategies and promising novel target RNAs. RNA Wire, 2010, 2, 32-41.

[55] Niebel B, Lentz C, Pofahl M, Mayer G, Hoerauf A, Pfarr KM, and Famulok M. ADLOC: an aptamer-displacement assay based on luminescent oxygen channeling. Chemistry – a European journal, 2010, 16, 11100-7.

[54] Ahmed MSL and Mayer G. Evolution of specific RNA motifs derived from pan-protein interacting precursors. Bioorg. Med. Chem. Lett., 2010, 20, 3793-3796.

[53] Mayer G & Wulffen B. The Chemical Biology of Aptamers: Synthesis and applications. The Chemical Biology of Nucleic Acids, Wiley-VCH (Ed. Mayer G.), 2010, 377-400.

[52] Heckel A & Mayer G. Light-responsive nucleic acids for the spatio-temporal control of biological processes. The Chemical Biology of Nucleic Acids, Wiley-VCH (Ed. Mayer G.), 2010, 279-306.

[51] Mayer G, Ahmed MSL, Dolf A, Endl E, Knolle P, and Famulok M. Fluorescent-activated cell-sorting for aptamer SELEX with composite cells. Nat. Protocols, 2010, 5, 1993-2004.

[50] Lünse CE, Michlewski G, Hopp C, Rentmeister A, Cacerés J, Famulok M, and Mayer G. An aptamer targeting the apical-loop domain modulates pri-miRNA processing. Angew. Chem. Int. Ed., 2009, 49, 4674-4677.

[49] Buff MC, Schäfer F, Wulffen B, Müller J, Pötzsch B, Heckel A, and Mayer G. Dependence of an aptamer on opposed terminal extension: improvement of light-regulation efficiency. Nucleic Acids Res., 2010, 38, 2111-2118.

[48] Mayer G, Butzen S, Lohberger A, Pofahl M, and Heckel A. From selection to caged aptamers: identification of light-dependent ssDNA aptamers targeting cytohesin. Bioorg. Med. Chem. Lett., 2009, 19, 6561-6564.

[47] Müller J, Mayer G und Pötzsch B. Maßgeschneiderte Moleküle durch Aptamertechnologie. Deutsche Zeitschrift für Klinische Forschung, 2009, 9/10, 52-55.

[46] Mayer G. Tiny tags on RNA. ChemBioChem, 2009, 10, 2145-2146.

[45] Klotz L, Burgdorf S, Dani I, Saijo K, Flossdorf J, Hucke S, Alferink J, Novak N, Beyer M, Mayer G, Langhans B, Klockgether T, Waisman A, Eberl G, Schultze J, Famulok M, Kolanus W, Glass C, Kurts C, and Knolle PA. The nuclear receptor PPARg selectively controls TH17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J. Exp. Med., 2009, 206, 2079-2089.

[44] Mayer G, Faulhammer D, Grättinger M, Fessele S, and Blind M. A RNA-based approach towards small molecule inhibitors. ChemBioChem, 2009, 10, 1993-1996.

[43] Mayer G. FACS-SELEX zur Identifikation zellspezifischer Aptamere. BIOspektrum, 2009, 3, 276-278.

[42] Siepmann M, Kumar S, Mayer G, and Walter J. Casein kinase 2 dependent phosphorylation of neprilysin regulates receptor tyrosine kinase signaling to Akt. PLoS one, 2010, 1, 5(10).

[41] Egler C, Brokemper O, Zabe-Kühn M, Mayer G, Oldenburg J, Schwaab R, and Albert T. Kinetic parameters of monoclonal antibodies ESH2, ESH4 and ESH8 on coagulation factor VIII and their influence on factor VIII activity. J. Mol. Recognit., 2009, 22, 301-306.

[40] Karadeniz H, Erdem A, Mayer G, Famulok M, and Caliskan A. Electrochemical sensing of aptamer-protein interactions using magnetic particle assay and single-use sensor technology. Electroanalysis, 2009, 21, 1278-1284.

[39] Mayer G, Müller J, Mack T, Freitag DF, Höver T, Pötzsch B, and Heckel A. Differential regulation of protein subdomain activity by caged bivalent ligands. ChemBioChem, 2009, 10, 654-657.

[38] Mayer G. The Chemical Biology of Aptamers. Angew. Chem. Int. Ed., 2009, 48, 2672-2689.

[37] Jayapal P, Mayer G, Heckel A, and Wennmohs F. Structure-activity relationships of a caged thrombin binding DNA aptamer: insight gained from molecular dynamics simulation studies. J. Struct. Biol., 2009, 166, 241-250.

[36] Müller J, Isermann B, Dücker I, Salehi M, Meyer M, Friedrich M, Madhusudhan T, Oldenburg J, Mayer G, and Pötzsch B. An exosite-specific ssDNA aptamer inhibits the anticoagulant functions of activated protein C and enhances inhibition by protein C inhibitor. Chem. Biol., 2009, 16, 442-451.

[35] Hunsicker A, Steber M, Mayer G, Meitert J, Klotzsche M, Blind M, Hillen W, Berens C, and Suess B. An RNA Aptamer that Induces Transcription. Chem. Biol., 2009, 16, 173-180.

[34] Mayer G and Famulok M. In vitro selection of conformational probes for riboswitches. Methods Mol. Biol., Springer Protocols, Humana Press Ltd. (in “Riboswitches: Methods and Protocols”, Vol. 540, Vol. Editor: Serganov A), 2009, 291-300.

[33] Höver T and Mayer G. In vitro selection of ssDNA aptamers using biotinylated targets. Methods in Mol. Biol., Springer Protocols, Humana Press Ltd. (in “Nucleic Acid and Peptide Aptamers: Methods and Protocols”, Vol. 535, Editor: Mayer G), 2009, 19-32.

[32] Müller J, Freitag D, Mayer G, and Pötzsch B. Anticoagulant characteristics of HD1-22, a bivalent aptamer that specifically inhibits thrombin and prothrombinase. J. Thromb. Haemost. 2008, 6, 2105-2112.

[31] Raddatz MSL, Dolf A, Endl E, Knolle P, Famulok M, and Mayer G. Enrichment of cell-targeting and population-specific aptamers by fluorescent-activated cell sorting. Angew. Chem. Int. Ed., 2008, 47, 5190-5193.

[30] Mayer G, Wulffen B, Huber C, Brockmann J, Flicke B, Neumann L, Hafenbradl D, Klebl BM, Lohse MJ, Krasel C, and Blind M. A RNA molecule that specifically inhibits G-protein-coupled receptor kinase 2 in vitro. RNA, 2008, 14, 524-534.

[29] Mayer G, Ackermann D, Kuhn N, and Famulok M. Construction of DNA architectures with RNA Hairpins. Angew. Chem. Int. Ed., 2008, 47, 971-973.

[28] Müller J, El-Maarri O, Oldenburg J, Pötzsch B, and Mayer G. Monitoring the progression of the in vitro selection of nucleic acid aptamers by denaturing high-performance liquid chromatography. Anal. Bioanal. Chem., 2008, 390, 1033-1037.

[27] Rentmeister A*, Mayer G*, Kuhn N, and Famulok M. Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides. Biol. Chem., 2008, 389, 127-134. (*Joint first author)

[26] Müller J, Wulffen B, Pötzsch B, and Mayer G. Multidomain targeting generates a high-affinity thrombin-inhibiting bivalent aptamer. ChemBioChem, 2007, 8, 2223-2226.

[25] Mayer G und Famulok M. Nukleinsäuren im Drug Discovery Prozess: Aptamere als Therapeutika am Beispiel Pegaptanib und als Werkzeuge zur Wirkstoffsuche. Pharm. unserer Zeit, 2007, 36, 432-436.

[24] Famulok M, Hartig JS, and Mayer G. Functional Aptamers and Aptazymes in biotechnology, diagnostic, and therapy. Chem. Rev., 2007,107, 3715-3743.

[23] Yamazaki S, Tan L, Mayer G, Song JN, Hartig J, Reuter S, Restle T, Kräusslich HG, Bajorath J, and Famulok M. Aptamer displacement identifies alternative small molecule target sites that escape viral resistance. Chem. Biol., 2007, 14, 804-812.

[22] Mayer G and Heckel A. Light-stimulated patterning of cells.ChemBioChem, 2007, 8, 857-858.

[21] Rentmeister A*, Mayer G*, Kuhn N, and Famulok M. Conformational changes in the expression domain of the thiM riboswitch. Nucleic Acids Res., 2007, 35, 3713-3722. (*Joint first author)

[20] Joachimi A, Mayer G, and Hartig J. A new anticoagulant-antidote pair: Control of thrombin activity by aptamers and porphyrins. J. Am. Chem. Soc., 2007,129, 3036-3037.

[19] Mayer G, Raddatz MSL, Grunwald JD, and Famulok M. RNA ligands that distinguish metabolite-induced conformations in the TPP riboswitch. Angew. Chem. Int. Ed., 2007, 46, 557-560.

[18] Heckel A, Buff MC, Raddatz MSL, Müller J, Pötzsch B, and Mayer G. An anticoagulant with light triggered antidote activity. Angew. Chem. Int. Ed., 2006, 45, 6748-6750.

[17] Mayer G and Heckel A. Biologically active molecules with “light switch”. Angew. Chem. Int. Ed., 2006, 45, 4900-4921.

[16] Famulok M and Mayer G. Aptamers in nanoland. Nature, 2006, 439, 666-668.

[15] Famulok M and Mayer G. Intramers for protein function analysis and drug discovery. In: The Aptamer Handbook - Functional Oligonucleotides and Their Applications. (Ed. S. Klussmann) VCH-Wiley, 2006.

[14] Mayer G and Famulok M. High-throughput-compatible assay for GlmS riboswitch metabolite dependence. ChemBioChem, 2006, 7, 602-604.

[13] Mayer G, Kröck L, Mikat V, Engeser M, and Heckel A. Light-induced formation of G-quadruplex DNA secondary structures. ChemBioChem, 2005, 6, 1966-1970.

[12] Heckel A and Mayer G. Light regulation of aptamer activity: an anti-thrombin aptamer with caged thymidine nucleobases. J. Am. Chem. Soc., 2005, 127, 822-23.

[11] Famulok M and Mayer G. Intramers and aptamers: Applications in protein function analyses and potential for drug screening. ChemBioChem, 2005, 6, 19-26.

[10] Mayer G and Jenne A. Aptamers in research and drug development. BioDrugs, 2004, 6, 351-359.

[9] Najafi-Shoushtari S H, Mayer G, and Famulok M. Sensing complex regulatory networks by conformationally controlled hairpin ribozymes. Nucleic Acids Res., 2004, 15, 3212-3219.

[8] Mayer G, Graettinger M, and Blind M. Aptamers: Multifunctional tools for target validation and drug discovery. Drug Plus, 2003, 2, 6-10.

[7] Mayer G, Grättinger M, and Blind M. Nucleic Acid Biotools: Accelerating the Discovery of Lead Compounds. Screening – Trends in Drug Discovery,2002, 6, 35-37.

[6] Blind M, Faulhammer D, and Mayer G. Speeding up functional genomics by automated selection of intramers. American Genomics/Proteomics Technology, 2002, 7/8, 28-33.

[5] Schurer H, Stembera K, Knoll D, Mayer G, Blind M, Forster H, Famulok M, Welzel P, and Hahn U. Aptamers that bind to the antibiotic moenomycin A. Bioorg. Med. Chem. 2001 Oct; 9(10):2557-63.

[4] Famulok M, Blind M, and Mayer G. Intramers as promising new tools in functional proteomics. Chem. Biol., 2001, 8, 931-939.

[3] Mayer G, Blind M, Nagel W, Böhm T, Knorr T, Jackson CL, Kolanus W and Famulok M. Controlling small guanine-nucleotide-exchange factor function through cytoplasmic RNA intramers. Proc. Natl. Acad. Sci. USA, 2001, 98, 4961-4965.

[2] Famulok M, Mayer G, and Blind M. Nucleic Acid Aptamers - From selection in vitro to applications in vivo. Accounts of Chemical Research, 2000, 33, 591-599.

[1] Famulok M and Mayer G. Aptamers as Tools in Molecular Biology and Immunology. In: Combinatorial Chemistry in Biology. Current Topics in Microbiology and Immunology (M. Famulok, C.-H. Wong, E.-L. Winnacker, Eds.), Springer Verlag, Heidelberg, 1999, 123-136.