gesamte Publikationen

Edwards-Faret G, de Vin F, Slezak M, Gollenbeck L, Karaman R, Shinmyo Y, Batiuk MY, Pando CM, Urschitz J, Rincon MY, Moisyadi S, Schnütgen F, Kawasaki H, Schmucker D, Holt MG. A New Technical Approach for Cross-species Examination of Neuronal Wiring and Adult Neuron-glia Functions.
Neuroscience. 2023; https://doi: 10.1016/j.neuroscience.2022.11.029.

Urwyler, O., Izadifar, A., Vandenbogaerde, S., Sachse, S., Misbaer, A., & Schmucker, D. (2019). Branch-restricted localization of phosphatase Prl-1 specifies axonal synaptogenesis domains. Science (New York, N.Y.), 364(6439), eaau9952.

Sachse, S. M., Lievens, S., Ribeiro, L. F., Dascenco, D., Masschaele, D., Horré, K., Misbaer, A., Vanderroost, N., De Smet, A. S., Salta, E., Erfurth, M. L., Kise, Y., Nebel, S., Van Delm, W., Plaisance, S., Tavernier, J., De Strooper, B., De Wit, J., & Schmucker, D. (2019). Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation. The EMBO Journal, 38(6), e99669.

Koch, M., Nicolas, M., Zschaetzsch, M., de Geest, N., Claeys, A., Yan, J., Morgan, M. J., Erfurth, M. L., Holt, M., Schmucker, D., & Hassan, B. A. (2018). A Fat-Facets-Dscam1-JNK Pathway Enhances Axonal Growth in Development and after Injury. Frontiers in cellular neuroscience, 11, 416.

Schmucker D. (2017). ABL to Integrate Opposing Cellular Growth Signals. Developmental Cell, 42(2), 108–109.

Oliva, C., Soldano, A., Mora, N., De Geest, N., Claeys, A., Erfurth, M. L., Sierralta, J., Ramaekers, A., Dascenco, D., Ejsmont, R. K., Schmucker, D., Sanchez-Soriano, N., & Hassan, B. A. (2016). Regulation of Drosophila Brain Wiring by Neuropil Interactions via a Slit-Robo-RPTP Signaling Complex. Developmental Cell, 39(2), 267–278.

Etlioglu, H. E., Sun, W., Huang, Z., Chen, W., & Schmucker, D. (2016). Characterization of a Single Genomic Locus Encoding the Clustered Protocadherin Receptor Diversity in Xenopus tropicalis. G3 (Bethesda, Md.), 6(8), 2309–2318.

Dascenco, D., Erfurth, M. L., Izadifar, A., Song, M., Sachse, S., Bortnick, R., Urwyler, O., Petrovic, M., Ayaz, D., He, H., Kise, Y., Thomas, F., Kidd, T., & Schmucker, D. (2015). Slit and Receptor Tyrosine Phosphatase 69D Confer Spatial Specificity to Axon Branching via Dscam1. Cell, 162(5), 1140–1154.

Petrovic, M., & Schmucker, D. (2015). Axonal wiring in neural development: Target-independent mechanisms help to establish precision and complexity. BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology, 37(9), 996–1004.

Urwyler, O., Izadifar, A., Dascenco, D., Petrovic, M., He, H., Ayaz, D., Kremer, A., Lippens, S., Baatsen, P., Guérin, C. J., & Schmucker, D. (2015). Investigating CNS synaptogenesis at single-synapse resolution by combining reverse genetics with correlative light and electron microscopy. Development (Cambridge, England), 142(2), 394–405.

Armitage, S. A., Sun, W., You, X., Kurtz, J., Schmucker, D., & Chen, W. (2014). Quantitative profiling of Drosophila melanogaster Dscam1 isoforms reveals no changes in splicing after bacterial exposure. PloS One, 9(10), e108660.

He, H., Kise, Y., Izadifar, A., Urwyler, O., Ayaz, D., Parthasarthy, A., Yan, B., Erfurth, M. L., Dascenco, D., & Schmucker, D. (2014). Cell-intrinsic requirement of Dscam1 isoform diversity for axon collateral formation. Science (New York, N.Y.), 344(6188), 1182–1186.

Kise, Y., & Schmucker, D. (2013). Role of self-avoidance in neuronal wiring. Current Opinion in Neurobiology, 23(6), 983–989.

Sun, W., You, X., Gogol-Döring, A., He, H., Kise, Y., Sohn, M., Chen, T., Klebes, A., Schmucker, D., & Chen, W. (2013). Ultra-deep profiling of alternatively spliced Drosophila Dscam isoforms by circularization-assisted multi-segment sequencing. The EMBO Journal, 32(14), 2029–2038.

Langen, M., Koch, M., Yan, J., De Geest, N., Erfurth, M. L., Pfeiffer, B. D., Schmucker, D., Moreau, Y., & Hassan, B. A. (2013). Mutual inhibition among postmitotic neurons regulates robustness of brain wiring in Drosophila. eLife, 2, e00337.

Schmucker, D., & Hassan, B. A. (2012). Hamlet Notches fate. Nature Neuroscience, 15(2), 174–176.

Meissirel, C., Ruiz de Almodovar, C., Knevels, E., Coulon, C., Chounlamountri, N., Segura, I., de Rossi, P., Vinckier, S., Anthonis, K., Deléglise, B., de Mol, M., Ali, C., Dassonville, K., Loyens, E., Honnorat, J., Michotte, Y., Rogemond, V., Smolders, I., Voets, T., Vivien, D., Schmucker, D., … Carmeliet, P. (2011). VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation. Proceedings of the National Academy of Sciences of the United States of America, 108(33), 13782–13787.

Chen, B. E., Kondo, M., Garnier, A., Watson, F. L., Püettmann-Holgado, R., Lamar, D. R., & Schmucker, D. (2006). The molecular diversity of Dscam is functionally required for neuronal wiring specificity in Drosophila. Cell, 125(3), 607–620.

Schmucker, D., & Chen, B. (2009). Dscam and DSCAM: complex genes in simple animals, complex animals yet simple genes. Genes & Development, 23(2), 147–156.

Wang, J.-H., Chen, Q., Meijers, R., Schmucker, D., Liu, J., Zhang, H. (2008). Decoding homophilic recognition specificity of Dscam, a neuronal receptor with thousands isoforms. Acta Crystallographica Section A Foundations of Crystallography. 64. C89-C89.

Collins, J., Arkus, N., Meng, G., Brenner, M., Schmucker, D., Manoharan, V. (2008). Complexity from Specificity: Light Scattering and Colloidal Studies of Dscam Self-Association.

Schmucker D. (2007). Molecular diversity of Dscam: recognition of molecular identity in neuronal wiring. Nature Reviews. Neuroscience, 8(12), 915–920.

Meijers, R., Puettmann-Holgado, R., Skiniotis, G., Liu, J. H., Walz, T., Wang, J. H., & Schmucker, D. (2007). Structural basis of Dscam isoform specificity. Nature, 449(7161), 487–491.

Hughes, M. E., Bortnick, R., Tsubouchi, A., Bäumer, P., Kondo, M., Uemura, T., & Schmucker, D. (2007). Homophilic Dscam interactions control complex dendrite morphogenesis. Neuron, 54(3), 417–427.

Kondo, M., Melcher, C., Erfurth, M.-L., Schmucker, D. (2006). Function and molecular diversity of the hypervariable receptor Dscam. Journal of Neurogenetics. 20. 148-148.

Chen, B. E., Kondo, M., Garnier, A., Watson, F. L., Püettmann-Holgado, R., Lamar, D. R., & Schmucker, D. (2006). The molecular diversity of Dscam is functionally required for neuronal wiring specificity in Drosophila. Cell, 125(3), 607–620.

Watson, F. L., Püttmann-Holgado, R., Thomas, F., Lamar, D. L., Hughes, M., Kondo, M., Rebel, V. I., & Schmucker, D. (2005). Extensive diversity of Ig-superfamily proteins in the immune system of insects. Science (New York, N.Y.), 309(5742), 1874–1878.

Schmucker, D., & Flanagan, J. G. (2004). Generation of recognition diversity in the nervous system. Neuron, 44(2), 219–222.

Schmucker D. (2003). Downstream of guidance receptors: entering the baroque period of axon guidance signaling. Neuron, 40(1), 4–6.

Schmucker, D., & Zipursky, S. L. (2001). Signaling downstream of Eph receptors and ephrin ligands. Cell, 105(6), 701–704.

Schmucker, D., Clemens, J. C., Shu, H., Worby, C. A., Xiao, J., Muda, M., Dixon, J. E., & Zipursky, S. L. (2000). Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell, 101(6), 671–684.

Schmucker, D., Vorbrüggen, G., Yeghiayan, P., Fan, H. Q., Jäckle, H., & Gaul, U. (2000). The Drosophila gene abstrakt, required for visual system development, encodes a putative RNA helicase of the DEAD box protein family. Mechanisms of Development, 91(1-2), 189–196.

Sheng, G., Thouvenot, E., Schmucker, D., Wilson, D. S., & Desplan, C. (1997). Direct regulation of rhodopsin 1 by Pax-6/eyeless in Drosophila: evidence for a conserved function in photoreceptors. Genes & Development, 11(9), 1122–1131.

Schmucker, D., Jäckle, H., & Gaul, U. (1997). Genetic analysis of the larval optic nerve projection in Drosophila. Development (Cambridge, England), 124(5), 937–948.

Schmucker, D., Su, A. L., Beermann, A., Jäckle, H., & Jay, D. G. (1994). Chromophore-assisted laser inactivation of patched protein switches cell fate in the larval visual system of Drosophila. Proceedings of the National Academy of Sciences of the United States of America, 91(7), 2664–2668.

Schmucker, D., Taubert, H., & Jäckle, H. (1992). Formation of the Drosophila larval photoreceptor organ and its neuronal differentiation require continuous Krüppel gene activity. Neuron, 9(6), 1025–1039.