Ausgewählte Publikationen

 

2025
  • Company-Garrido, I., Carpio, A. Z., Colomer-Rosell, M., Ciraulo, B., Molkenbur, R., Lanzerstorfer, P., Pezzano, F., Agazzi, C., Hauschild, R., Jain, S., Jacques, J. M., Venturini, V., Knapp, C., Xie, Y., Merrin, J., Weghuber, J., Schaaf, M., Quidant, R., Kiermaier, E§., Arroyo, J§. O., Ruprecht, V§. & Wieser, S§. Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses. Dev. Cell (2025). doi:10.1016/j.devcel.2025.10.006 §corresponding authors
     
  • Schlautmann, L., Burgdorf, D., Ghosh, S., Schieren, A., Klümpen, L., Stötzel, I., Bremser, J., Döngi, M., Mass, E., Stein, V., Quast, T., Kolanus, W., Lang, T., Kiermaier, E., Simon, M.-C., Burgdorf, S., Glucose tasting depletes intracellular calcium stores and impairs macrophage functionality, iScience (2025), doi: https://doi.org/10.1016/j.isci.2025.113770.   
     
  • Schmitt, M. T., Kroll, J., Ruiz-Fernandez, M. J. A., Hauschild, R., Ghosh, S., Kameritsch, P., Merrin, J., Schmid, J., Stefanowski, K., Thomae, A. W., Cheng, J., Öztan, G. N., Konopka, P., Ortega, G. C., Penz, T., Bach, L., Baumjohann, D., Bock, C., Straub, T., Meissner, F., Kiermaier, E. & Renkawitz, J. (2025) Protecting centrosomes from fracturing enables efficient cell navigation. Science Advances 11, eadx4047 
     
  • Wurnig, S. L., Huber, M. E., Weiler, C., Baltrukevich, H., Merten, N., Stötzel, I., Steffen, T., Chang, Y., Klammer, R. H. L., Baumjohann, D., Kiermaier, E., Kolb, P., Kostenis, E., Schiedel, M. & Hansen, F. K. (2025) A Fluorescent Probe Enables the Discovery of Improved Antagonists Targeting the Intracellular Allosteric Site of the Chemokine Receptor CCR7. Journal of Medicinal Chemistry doi:10.1021/acs.jmedchem.4c02102

2024
  • Kiermaier, E§., I. Stötzel, M.A. Schapfl, and A. Villunger§. Amplified centrosomes—more than just a threat. EMBO Reports (2024) 1–15. doi:10.1038/s44319-024-00260-0 
     
  • Isabel Stötzel, Ann-Kathrin Weier, Apurba Sarkar, Subhendu Som, Peter Konopka, Eliška Miková, Jan Böthling, Mirka Homrich, Laura Aradilla-Zapata, Ulrich Kazmaier, Konstantinos Symeonidis, Zeinab Abdullah, Stefan Uderhardt, Miroslav Hons, Raja Paul, Heiko Rieger*Eva KiermaierMultiple clustered centrosomes in antigen-presenting cells foster T cell activation without MTOC polarization. BioRxiv 
    doi: https://biorxiv.org/cgi/content/short/2024.07.18.604057v1
     
  • Schapfl MA, LoMastro GM, Braun VZ, Hirai M, Levine MS, Kiermaier E, Labi V, Holland AJ. & Villunger A. Centrioles are frequently amplified in early B cell development but dispensable for humoral immunity. Nat. Commun. 15, 8890 (2024). 
     
  • Kayvanjoo AH, Splichalova I, Bejarano DA, Huang H, Mauel K, Makdissi N, Heider D, Tew HM, Balzer NR, Greto E, Osei-Sarpong C, Baßler K, Schultze JL, Uderhardt S, Kiermaier E, Beyer M, Schlitzer A, Mass E. (2024) Fetal liver macrophages contribute to the hematopoietic stem cell niche by controlling granulopoiesis. eLife. Mar 25;13:e86493. doi: 10.7554/eLife.86493. 

2022
  • Stötzel I and Kiermaier E. (2022) Phagocytosis: The central role of the centrosome. eLife doi.org/10.7554/eLife.84659
     
  • Weier AK*, Homrich M*, Ebbinghaus S, Juda P, Miková E, Hauschild R, Zhang L, Quast T, Mass E, Schlitzer A, Kolanus W, Burgdorf S, Gruß OJ, Hons M, Wieser S, Kiermaier E§.  (2022) Multiple centrosomes enhance migration and immune cell effector functions in mature dendritic cells. Journal of Cell Biology 221 (12): e202107134. doi.org/10.1083/jcb.202107134
     
  • Quast T, Zölzer K, Guu D, Alvarez L, Küsters C, Kiermaier E, Kaupp UB, Kolanus W. (2022). A Stable Chemokine Gradient Controls Directional Persistence of Migrating Dendritic Cells. Front Cell Dev Biol 10. doi:10.3389/fcell.2022.943041
     
  • Paul Kern, Nora R. Balzer, Nelli Blank, Cornelia Cygon, Klaus Wunderling, Franziska Bender, Alex Frolov, Jan-Peter Sowa, Lorenzo Bonaguro, Thomas Ulas, Mirka Homrich, Eva Kiermaier, Christoph Thiele, Joachim L. Schultze, Ali Canbay, Reinhard Bauer, Elvira Mass. Creld2 function during unfolded protein response is essential for liver metabolism homeostasis. FASEB J.  (2021); 35:e21939. doi:10.1096/fj.202002713RR

2021-2020
  • Aglaja Kopf and Eva Kiermaier* (2021). Dynamic microtubule arrays in leukocytes and their role in cell migration and immune synapse formation. Frontiers in Cell and Developmental Biology 9:635511. doi: 10.3389/fcell.2021.635511
     
  • Kopf A, Renkawitz J, Hauschild R, Girkontaite I, Tedford K, Merrin J, Thorn-Seshold O, Trauner D, Häcker H, Fischer KD, Kiermaier E*§, Sixt M. (2020) Microtubules control cellular shape and coherence in amoeboid migrating cells. Journal of Cell Biology Jun 1; 219(6):e201907154.

before 2020
  • Kiermaier E*§, Moussion C*, Veldkamp CT, Gerardy-Schahn R, de Vries I, Williams LG, Chaffee GR, Phillips AJ, Freiberger F, Imre R, Taleski D, Payne RJ, Braun A, Förster R, Mechtler K, Mühlenhoff M, Volkman BF, Sixt M.§ (2016) Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science 351(6269):186-190. 
     
  • Kiermaier E, Sixt M. (2015) Immunology. Fragmented communication between immune cells. Science349(6252):1055-6.
     
  • Molatore S, Kiermaier E, Jung CB, Lee M, Pulz E, Höfler H, Atkinson MJ, Pellegata NS. (2010) Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors. Molecular Cancer 9:116.
     
  • Kiermaier E, Woehrer S, Peng Y, Mechtler K, Westermann S. (2009) A Dam1-based artificial kinetochore is sufficient to promote chromosome segregation in budding yeast. Nature Cell Biology 11(9):1109-15
     
  • Kowarik M, Numao S, Feldman MF, Schulz BL, Callewaert N, Kiermaier E, Catrein I, Aebi M. (2006) N-linked glycosylation of folded proteins by the bacterial oligosaccharyltransferase. Science 314(5802):1148-50. doi: 10.1126/science.1134351.

​​​​​​
*equally contributing authors. §corresponding authors.